Antibacterial Activity and Toxicity of the Sap and Aqueous Extract of the Leaves of <i>Jatropha multifida</i> Linn

Introduction: Jatropha multifida Lin was a plant of traditional Beninese medicine used as an antibiotic. This study aimed to evaluate the antibacterial activity and toxicity sap aqueous extract leaves. Methods: Phytochemical screening leaves carried out. The obtained by maceration. antimicrobial evaluated on five strains hospital germs. Acute oral forced gavage in single dose 2000 mg/kg body weight performed female Wistar rats. Biochemical hematological parameters were determined. Results: presence flavonoids, tannins, alkaloids, anthocyanins, mucilages, leuco-anthocyanins saponosides noted multifida. extracts inhibited two Staphylococcus aureus out three, while 100% bactericidal against Streptococcus D. leaf not Escherichia coli, Klebsiella oxytoca Pseudomonas aeruginosa. For toxicity, there no death rats did significantly vary rats, creatinine, ALAT transaminase, hemoglobin level, number white blood cells platelets. Conclusion: exerted more effective than its acutely toxic.